nuthinbutpink
April 15th, 2011, 08:08 AM
Hi Carole! I am not sure if this falls within your realm of experience but I thought I would try. When researching PGD and probes, I can across a site that had this info-
"Apart from these five chromosomes (13, 18, 21, X, Y), the only other chromosomes noticeably affecting the outcome of established pregnancies are chromosomes 16 (trisomy 16 found in 1,229 among 15,000 spontaneous abortions) and 22 (extra copy was present in 424 out of 15,000 spontaneous abortions). These embryos never reach term, but they affect the outcome of hurnan pregnancies.
Aneuploidy for any other chromosome is lethal at the very first stages of embryo development, before a pregnancy can even be established."
So, if I read this right, according to this center, outside of a 5 probe and chromosome 16 and 22, a pregnancy will never even establish? So, if one were to do a 5-probe(X, Y, 21, 18, 13), the only chance of miscarriage would be on 16 and 22? Any other issue on another chromosome will just not implant? Am I reading that right? Do you know this to be true?
Thanks and hope you are doing well!
"Apart from these five chromosomes (13, 18, 21, X, Y), the only other chromosomes noticeably affecting the outcome of established pregnancies are chromosomes 16 (trisomy 16 found in 1,229 among 15,000 spontaneous abortions) and 22 (extra copy was present in 424 out of 15,000 spontaneous abortions). These embryos never reach term, but they affect the outcome of hurnan pregnancies.
Aneuploidy for any other chromosome is lethal at the very first stages of embryo development, before a pregnancy can even be established."
So, if I read this right, according to this center, outside of a 5 probe and chromosome 16 and 22, a pregnancy will never even establish? So, if one were to do a 5-probe(X, Y, 21, 18, 13), the only chance of miscarriage would be on 16 and 22? Any other issue on another chromosome will just not implant? Am I reading that right? Do you know this to be true?
Thanks and hope you are doing well!