nancy
June 25th, 2011, 05:07 PM
Hi Dr. Potter,
I will be cycling with you in August. You recommended GSN for me (I am on the long lupron protocal, age 38 and doing GS for a girl). I am very excited about this relatively new technology but feeling a little apprehensive as well. There have been mixed comments about GSN vs. FISH (2,5,9-probe) on this board. I have a few questions below that I hope you will not mind answering. If it is easier to speak on the phone w/yourself or Lori please let me know.
1. I was wondering if you will still recommend GSN for me if I have 10 or less healthy embryos to work with?
2. There has been concern that since GSN tests a single cell on day three that it isn't the most reliable method of testing compared to day 5 w/FISH. Can you provide me with reassurance that it in fact is?
3. You posted on another thread that 5-probe "With FISH (2, 5 or 9 probe), you are looking at around 50% of the embryos that are thought to be normal actually having abnormalities in one or more of the chromosomes that have not been checked". How often does this scenario happen with woman my age who do not have a history of inherited genetic diseases or any fertility issues? My main concerns are preventing downs, trisomy, etc...
4. Are you seeing more successful pregnancies achieved w/FISH (2, 5 or 9 probe) or GSN?
5. Lastly, I would like some reassurance about 24 chromosome testing since it is a relatively new technology. Since you are the lab director at GSN, I am hoping this means you work w/the same highly trained staff on a regular basis who are experts with this?
Thank you in advance for your response! I am really looking forward to hearing from you!
I will be cycling with you in August. You recommended GSN for me (I am on the long lupron protocal, age 38 and doing GS for a girl). I am very excited about this relatively new technology but feeling a little apprehensive as well. There have been mixed comments about GSN vs. FISH (2,5,9-probe) on this board. I have a few questions below that I hope you will not mind answering. If it is easier to speak on the phone w/yourself or Lori please let me know.
1. I was wondering if you will still recommend GSN for me if I have 10 or less healthy embryos to work with?
2. There has been concern that since GSN tests a single cell on day three that it isn't the most reliable method of testing compared to day 5 w/FISH. Can you provide me with reassurance that it in fact is?
3. You posted on another thread that 5-probe "With FISH (2, 5 or 9 probe), you are looking at around 50% of the embryos that are thought to be normal actually having abnormalities in one or more of the chromosomes that have not been checked". How often does this scenario happen with woman my age who do not have a history of inherited genetic diseases or any fertility issues? My main concerns are preventing downs, trisomy, etc...
4. Are you seeing more successful pregnancies achieved w/FISH (2, 5 or 9 probe) or GSN?
5. Lastly, I would like some reassurance about 24 chromosome testing since it is a relatively new technology. Since you are the lab director at GSN, I am hoping this means you work w/the same highly trained staff on a regular basis who are experts with this?
Thank you in advance for your response! I am really looking forward to hearing from you!