Free β-hCG and PAPP-A levels and baby's gender

[Mum to three girls]

It wasn't right for me. My HCG was 2.5 MoM and my PAPP-A was 0.7. They were such weird bloods I had one of those blood tests where they look for trisomies and I am having a healthy boy.

[Mum to three girls]

I should add that my HCG was huge from the onset and I haven't had even a tiny bit of sickness - completely different to the previous three.

[BunnyGirl19]

Did you have any bleeding early on? That is known to cause elevated hCG levels and often accounts for women getting a high risk result on the screen with a chromosomally normal baby.

Also, the study isn't specifically wrong for you. BOTH numbers either elevated or low are needed for determining gender by this method. Of course there are going to be those that don't fit the pattern. You had a very girl HCG level but a very boy PAPP-A level. Because of that, it could go either way. I don't know what your NT measurement was.

[Mum to three girls]

Did you have any bleeding early on? That is known to cause elevated hCG levels and often accounts for women getting a high risk result on the screen with a chromosomally normal baby.

Also, the study isn't specifically wrong for you. BOTH numbers either elevated or low are needed for determining gender by this method. Of course there are going to be those that don't fit the pattern. You had a very girl HCG level but a very boy PAPP-A level. Because of that, it could go either way. I don't know what your NT measurement was.

No, no bleeding. I've been completely well. My NT measurement was lower than average though. From memory my HCG was higher than ave but not as high with my girl pregnancies. My PAPP-A has always been a bit lower than average. The combination of high HCG and low PAPP-A put my Down Syndrome risk from the bloods alone at 1:30. The overall risk was much lower because of the normal scan but that's why I got nervous and had the blood test done.

[glory]

Did you have any bleeding early on? That is known to cause elevated hCG levels and often accounts for women getting a high risk result on the screen with a chromosomally normal baby.

My HCG MOM was almost 8 times higher than average but the Papp A was also 4 times higher, so I had a very low risk of any abnormalities.

But I did have a lot of bleeding in the first trimester, how does that affect the HCG? No one ever mentioned that to me. Would it increase the Papp A at the same time?

[BunnyGirl19]

I work in perinatology and when there is bleeding in pregnancy hCG levels typically elevate because the placenta is trying to hold onto the pregnancy. It's not really understood why it goes up, but we tend to think it's the body trying to correct a problem and stop the bleeding. We haven't seen that it has a direct effect in PAPP-A levels though. Most commonly in women with bleeding we see high HCG and a normal level of PAPP-A (meaning not a super low one in the risk zone) and as a result this triggers a high risk on the Down's screening since high HCG and low PAPP-A are soft markers for Down's. Another thing with the hormone levels we don't know a reason for is that women who have had IVF have much, much higher levels of both hormones than a natural pregnancy, so this study wouldn't fit a pattern for determining gender in that instance.

[divi08]

Probably boy.....

This theory is right for me..It's a BOY! Jark22 - you were right..
Thank you!!!

[NERI]

just got my results back,any gender clues?DSC_0140.JPGthanks

[NERI]

anyone?

[NeedBlessings]

Hi all help me with my readings
Mine read as Free beta HCG - 0.44 MoM
PAPP-A- 0.72 MoM, NT MoM 0.97 and CRL 64 mm
its boy or girl?