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If you think the Benadryl works better for you, Benadryl it is! I just can't stand the way Benadryl makes me feel and I'm not exactly a demon in the sack after I take it LOL.

You CAN mix Benadryl with Zyrtec if you want - they act on different parts of the body and they are safe to mix (corroborated by allergist and pharmacist)