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I should say it does leave your body but the effects of the spironolactone stick around for much longer. Please whatever you do wait for at least 6-8 weeks before TTC!!!


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I personally wouldn't take the risk with this drug when it is known to cause birth defects but that is just me. It just isn't worth the risk to me. I absolutely loved the Spiro when I was on it though!!! There are plenty of links/sites/forum posts online where others were also told to wait the 6-8 weeks.

I am not sure about the saw palmetto. I don't think you would need it as the Spiro will do a much better job of lowering your T levels than SP will. Do you only take SP to lower testosterone levels or what else does it do?

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I am sure you could ask someone at the drug company but be forewarned that they are there to sell drugs not really to help patients. LOL! I am not against pharm companies at all, I am just not sure they are the best to ask about it. For me it was an easy decision after so many people were told to wait the 6-8 weeks before TTC. I just couldn't move forward knowing a ton of other people had been told to wait that long when I was told the exact same thing. I may have felt differently had I been told to only wait a week but what I was told was the general feeling I also got from the internet.

Lowering your testosterone will also lower your estrogen levels. If you decrease your hormone levels too much there is a chance it could really throw things off. I am not sure that I would take both of them together but I don't know enough about SP to be certain.

Actually sometimes lowering testosterone means your body takes the raw materials it was making into testosterone, and starts making them into estrogen, so estrogen can rise when T is lowered and vice versa.

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Yes and in fact we've had to drop some sway supps because of it. Does no good to raise your T if you have no CM (blue swayers, that is!!) :) Balding guys try to lower their T levels in order to stop their hairloss and end up growing boobs due to the increase in estrogen. Clomid also raises T but lowers E.

Now that may not be how spirolactone works, just that I do know it's not always so cut and dry with T and E - they interact in somewhat mysterious and unpredictable ways and there are def. times when lowering one can cause the other to rise.

Personally, I agree with Michaela and would stop the Spiro in ample time to ensure it is out of the system first. I do not think that you're going to see a mega-rise in T but I don't know of anyone who has gone off spiro so I can't totally say firsthand.

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I was on it for about a year or a year and half before I went off of it. It did take some time but yes my testosterone levels went back up. It made my hormonal acne go away (that was on the base of my hairline when I got my period) as well as cleared up my oily skin. It did not take away the little blonde chin hairs I get though!

Are you on Metformin? That will do just as good of a job as the spiro in lowering your T levels and it will help with your insulin resistance. If you are not on it, is there a reason especially with the known insulin issues?

I say go off of it as far in advance as you can. There are other ways to lower your T levels that won't cause birth defects.