Dr Potter question

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Originally Posted by GT77

I don't know any place in NYC that offers GSN. Do you?

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SIRM does.

http://haveababy.com/fertility-clini...tility-clinic/

And yes we used ICSI.


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I guess I'd like to say at a certain point, if trying to find a clinic that does GSN is too stressful for you, you're better off finding a reputable clinic that's close to you. Lots of women have flown from around the world with kids and husbands to see Dr. Potter so it is possible, but if it doesn't work for you and your family- don't do it. You sound very stressed about this and the stress won't help you in your cycle. So maybe finding the least stressful option is best for you.

I do really want to stress though that going into the cycle thinking it MUST work in that one cycle will only set you up for heart ache. Sure, there are some one hit wonders on here but more often than not, the first cycle doesn't go as planned because your body responds differently to the meds or whatever. So worrying about what to freeze is premature at this point. Certainly, things could go great and you'll be a OHW but please know that even at your age, you have to prepare yourself for having NOTHING to transfer. Just want you to be prepared is all...

You are 100% correct. I know, I do want to have it work & since it is out of pocket there is no way I can get my hubby to pay for 2 rounds at NYU. I guess, if it didn't work I can always go to Dr.Potter office & as you said it exactly " I can make it work". I wish Dr. Potter prices were the same here in New York. I find it crazy that NY prices are so much higher than California. Let me just ask you guys another question, & thank you so much for all your support. NYU wants to do Acgh on Day 5, & FET. Do you think that doing a Fresh on day 6, is a wise decision or that I may lose some good embryo's & it is too risky? If this does not work & you are right it may not, then I will have no choice, but to walk away. I do have a healthy little boy at home.

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Originally Posted by GT77

Hi Dr. Potter,

I know you believe that Day 3 GSN is the same as Day 5 acgh. Actually, you have posted that GSN is more detailed than acgh will ever be. I understand that part of why you think that.

I need you to explain to me why a million people keep on saying that a Day 3 embryo can fix themselves into a healthy embryo on day 5. But, if we did GSN on day 3, and it came back abnormal, how would I ever know if that "abnormal embryos", may of had the chance to "fix itself by day 5". That is the whole theory behind the 5 day blastocyst stage that is why NY state is pushing it so hard. It gives the embryo's time to fix themselves in case they are abnormal.

You are a firm believer in Day 3. You believe that any embryo on day 3, that is tested by GSN & comes up abnormal, can never correct itself?
Your theory goes against what everyone is saying in NY State. In NY everyone says to do blastocyst on Day 5 with ACGH & there is an option for Day 6 fresh embryo. I am assuming you Freeze your embryo's on Day 5 & as well as the Blastocyst. So, the only difference is that GSN tested on Day 3 you can put in a "fresh embryo on day 5" vrs a blastocyst you can put a fresh embryo on day 6".
Also, I need you to explain to me why all the GSN testing done on Day 3 is 100 accurate & why testing on Day 5 for Acgh is a waste of time. And, why are so many people claiming that, the testing is better on Day 5 because cells can correct themselves. Are you claiming whoever gets the GSN test done on Day 3, means that all those embroys that were tested abnormal, are abnormal & they can never correct themselves into being a "normal embryo".

I understand that GSN is an amazing test that can test for all 24 Chromosomes on Day 3 & the best part you can have a fresh embryo on day 5, that if that did not work you would then do FET if you want. I know you also have packages.

What day do you freeze the extra embryos on? Is it day 5 or day 3? IN New york, they freeze the embryo's on day 5. Is the only difference between you & NY is that you do a Day 5 transfer & NY does a Day 6 transfer? Are you saying that GSN you can never make a mistake for any abnormal embryos??

In NY you can do blastocyst to day 5, test for Acgh, & then transfer a fresh transfer on day 6.

Why does the rest of the world feel that blastocyst to stage 5 is the best way to go? Why aren't more people using GSN over ACGH, if it is better?

Are you saying that GSN is 100% accurate on day 3?

I understand that ACGH isn't accurate on day 3, because I heard the gender is not always correct and that their are false positives and now no one will use ACGH on day 3 in New York State.
So, if GSN is proven to be 100% accurate, then why isn't everyone using it? Why do people in NY feel that the day 5 blastocyst stage is the only way to go? This is really so confusing. NYU, told me I could use GSN if i wanted. But, they told me ACGH is better. Why?

Why wouldn't they tell me to use GSN, if GSN is better on day 3 & best part I can have a fresh transfer? I would hope that their goal is to get me pregnant with a healthy baby, not for me to wait to blastocyst stage. Please share your thoughts for all of us!

I really need to know which outcome will end up with the most females since I am doing PGD for gender?
What day do you freeze your extra embryos after a fresh cycle?

Do you feel that if I did a blastocyst for Female Gender, using ACGH, would it be in my best interest to do a Day 6 fresh transfer or does it not matter & I should do a Frozen Transfer. Do you feel I will have more girls with GSN test on Day 3, then I would with ACGH test on Day 5? Should one day make that much of a difference if they are healthy?

Please let me know your advice & I will be planning a consult with you via skype very soon!

Thank you,
GT

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These are great questions. The weakness of Natera day 3 is that due to mosaicism, some embryos that are not normal will be normal with day 5 biopsy. Because Natera is detecting abnormalities that aCGH does not, the advantage of day 5 aCGH is mitigated. Ultimately, I think that Natera day 3 and aCGH on day 5 are similar and we in fact use both. I also think that ultimately day 5 Natera will prove to be the gold standard when it become available because it will offer the advantages of both Natera and day 5.

The Natera technology is extremely accurate on day 3 with not one gender opposite. aCGH has trouble with the small chromosomes one of which is the Y chromosome. Other centers have invested heavily in technology that works only on day 5 and do not offer competing technologies. We offer Natera as well as day 5 aCGH. I am committed to Natera's technology but ultimately am more committed to doing whatever is going to give my patients the very best probability for pregnancy. Right now that is Natera day 3 in most cases at our center.

Neither technique will give more females than the other.

We freeze the extra embryos on day 5.

Since NY has come up in this topic does anyone know what type of PGD and transfer (fresh, frozen) RMANY does? I'm trying to get a consult scheduled with them but haven't found that out yet. I'd really prefer a fresh, single embryo transfer if possible. I am 27 now but will probably be 28 by the time of the cycle and I'm not sure whether to test for gender only or more than that at my age?

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Originally Posted by rh1985

Since NY has come up in this topic does anyone know what type of PGD and transfer (fresh, frozen) RMANY does? I'm trying to get a consult scheduled with them but haven't found that out yet. I'd really prefer a fresh, single embryo transfer if possible. I am 27 now but will probably be 28 by the time of the cycle and I'm not sure whether to test for gender only or more than that at my age?

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I know that Dr. Copperman was using Natera in the past. I would ask him. He is one of the honchos there, a straight up guy and great doctor.

Dr Potter can you please explain the success rate for gender of aCGH at day 5. We have a cycle planned with you for this but need to know we will be assured our xx. Thanks

Bump