FAILED first cycle with HRC, need advise before cycle 2 PLEASE!!
Hi Ladies,
I would appreciate your help. Is there anything I could try for cycle 2 for a better chance of success, or are my chances poor (please be honest, this process has been heart breaking)? Any recommendations would really be appreciated!
I am 36, DH is 37.
My day 3 pretesting results were:
AFC = 15
FSH = 6.2IU/L
AMH = 4.94ng/ml or 35.3pmol/L
estradiol = 119pmol/L or 32.4pg/mL
LH = 6.56IU/L
My TSH was high at 5.8, am on eltroxin and was down to 2.8 before ER.
VITAMINS = ubiquinol 600mg, fish oil, prenatal vitamin. Diet was low carb, high protein. drinking decaf and no alcohol.
My BMI is 22.4.
DH's results were poor - below normal in every category except for volume. It surprised us as we have 2 kids and never suspected we had any fertility issues.
My medications were:
BCP for 20 days, started 1st september
started 5 units of buserelin on the 16th september
Started Gonal F 150IU and menopur 75IU, and 2.5 units of buserelin on the 26th September.
Estradiol measured on 22th September as under 18pmol/L and on the 29th September as 1356pmol/L.
30th September - Gonal F reduced to 125 - other meds stayed the same
3rd October, estradiol = 2075, progesterone = 0.604ng/ml. Gonal F reduced to 75 - other meds stayed the same
4th october, estradiol = 2393, progesterone = 0.647ng/ml.
5th October - egg retrieval - 23 eggs retrieved, 17 fertilised, only 3 made it to day 5 biopsy - all opposite gender and only one normal.
Things I am thinking...... my AMH looks high, i have never been diagnosed with PCOS but have always had irregular periods. Insulin resistance test done and it was fine. could i be borderline PCOS?
The dramatic drop from 17 to 3 eggs - i believe they were doing ok until day three - is this down to poor sperm. Last cycle icsi was done, is this enough?
one last thought - was my increase in estradiol too fast? does that make a difference?
Thanks a million xx