Results 1 to 7 of 7
  1. #1

    Hatching blast after PGD not a "true HB" ???

    I am curious to hear your thoughts on this. My RE dampened my excitement at seeing 2 hatching blasts this morning by stating that an embryo that has undergone PGD and is hatching is not a true hatching blast because it has been given an exit point by which to hatch. What are your thoughts on this statement? Is a PGD'd hatching blast less superior than a natural hatching blast? Thanks!
    Mommy to 7 and 5, born 1/26/12!

    Cycle 3 BFP with Dr. Lin @ RFC!

  2. #2
    Site Owner
    nuthinbutpink's Avatar
    Join Date
    Dec 2010
    Location
    The Internet
    Posts
    24,572
    I think that is BS. Then why are some that have been biopsied still morulas??? Ask him that.

    Sorry. Just saw this is in Carole's forum.
    Mom to

    and my IVF/PGD

    Become a Dream Member to access the private forums

  3. #3
    Quote Originally Posted by nuthinbutpink View Post
    I think that is BS. Then why are some that have been biopsied still morulas??? Ask him that.

    Sorry. Just saw this is in Carole's forum.
    I think he is being overly conservative with me after over promising at my last transfer, to be perfectly honest. No apologies necessary on the location LOL.
    Mommy to 7 and 5, born 1/26/12!

    Cycle 3 BFP with Dr. Lin @ RFC!

  4. #4
    Gentle bump.
    Mommy to 7 and 5, born 1/26/12!

    Cycle 3 BFP with Dr. Lin @ RFC!

  5. #5
    Dear winogurl,
    I have no earthly idea what he means by not a "true hatching blast". If the embryo fails to grow, it will not increase in cell number and will not merely "fall out" of the cavity produced by the hatching procedure. A blast that grows properly will have an expanding blastocoel- a fluid filled cavity - and an increasing number of cells specialized into either the trophectoderm layer or inner cell mass. This increase in girth is what normally causes the (zona pellucida) shell to thin and split, allowing the embryo to escape. Those morphological signs of normal progression are what's important, not how hard the embryo has to work to split out of the shell and escape. I don't know what he is getting at. Here's a post with lots of embryo pics on the topic of embryo progression that may help: http://fertilitylabinsider.com/2010/...s-progression/
    Carole

    Like my blog? Check out the ebook, Fertility Lab Insider,
    now available through Amazon (Kindle) and Barnes & Noble Booksellers (Nook)
    Fertility Lab Insider | http://www.amazon.com/dp/B004QOB7Z8

  6. #6
    Site Owner
    nuthinbutpink's Avatar
    Join Date
    Dec 2010
    Location
    The Internet
    Posts
    24,572
    Quote Originally Posted by Carole View Post
    Dear winogurl,
    I have no earthly idea what he means by not a "true hatching blast". If the embryo fails to grow, it will not increase in cell number and will not merely "fall out" of the cavity produced by the hatching procedure. A blast that grows properly will have an expanding blastocoel- a fluid filled cavity - and an increasing number of cells specialized into either the trophectoderm layer or inner cell mass. This increase in girth is what normally causes the (zona pellucida) shell to thin and split, allowing the embryo to escape. Those morphological signs of normal progression are what's important, not how hard the embryo has to work to split out of the shell and escape. I don't know what he is getting at. Here's a post with lots of embryo pics on the topic of embryo progression that may help: http://fertilitylabinsider.com/2010/...s-progression/
    Carole

    Like my blog? Check out the ebook, Fertility Lab Insider,
    now available through Amazon (Kindle) and Barnes & Noble Booksellers (Nook)
    Fertility Lab Insider | http://www.amazon.com/dp/B004QOB7Z8
    So, I was right about the B.S.!
    Mom to

    and my IVF/PGD

    Become a Dream Member to access the private forums

  7. #7
    Quote Originally Posted by nuthinbutpink View Post
    So, I was right about the B.S.!
    Certainly sounds that way!!! Of course, I am thrilled to hear this!
    Mommy to 7 and 5, born 1/26/12!

    Cycle 3 BFP with Dr. Lin @ RFC!

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •