Unisom (doxylamine succinate) + B6 helps quite a bit. Zofran never helped me The only thing that completely cured my morning sickness was when I was on the hospital IV... BUT with this little one I took a tablespoon full of coke syrup every morning and it really helped! If was HORRIBLE to take, but I felt so good I forced myself to take it. I also would pour coke syrup over ice and sip on it throughout the day as well. It was the only thing that worked. I did eat beans during my first trimester but my MS got so severe I could not even stand their texture without gagging. I hope you find something that works! I'm 18 weeks today and still deal with it on a nightly basis.