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  1. #11
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    Keep in mind, in that case, that if something were to go wrong (such as a loss, G-- forbid, or a side effect - we have only ever had mild ones, or an allergic reaction - never had one happen but they are possible) and you're in the ER with him, they're going to ask you what medication you were on if any and then that puts you in a heck of an awkward position.

    Femara did seem better in one study, but studies are funny things in that sometimes one will say one thing, and another study will say the opposite. There are more studies that support Clomid on its own, and only the one in which it was compared to Femara.

    I believe Femara is better, although it can be harder to come by as not all docs are willing to prescribe it.
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  2. #12
    Quote Originally Posted by SoFullofHope View Post
    Dear Verena,

    I just looked it up again and, contrary to what I wrote, the risk of malformations seems to be greater with Clomid. A study from April(?) 2016 found malformations in 2.4% of babies conceived with Femara and 4.8% of babies conceived with Clomid! I had asked both my local gynaecologist and Clinic C about the malformation risk when taking Femara and they both confirmed that it is indeed true.
    However, what you probably have to take into account as well is that it's mainly older women and women with fertility problems who take these drugs. With us, the risk of malformations is higher anyway, so some of it might simply be due to our age and the bad egg quality, not necessarily always due to Femara or Clomid.

    Yeah, stupidly, we're in a rather complicated situation and can only get one attempt (two max.) per cycle in :-(
    At least I can tell you in the meantime that, for me, it didn't work this cycle: I had three follicles but despite two attempts before and on the day of ovulation, not one of these eggs got fertilised :'-( (or if they did, they didn't implant).
    The hormones did mess with my cycle though. Injecting them was fine (DH gladly did so) and except for an upset stomach the first time I took Menopur and me being rather emotional while taking them, that was the easy bit. But I'm not sure at all if I really ovulated when they predicted it or rather one day earlier or later (as I did feel it twice, just not in the window predicted by the doctors), and then I got my period late and my hopes up, but I got a BFN yesterday and AF arrived this afternoon :'-(
    As I've also got a yeast infection which I think is also due to all the hormones I took, I think I'll give it a break this month (also in order to take some ubiquinol, hoping it'll improve my egg quality) but if I continue next month or the month after and it works after all, I'll let you know :-)

    Really good luck to you too!!
    Dear SoFullofHope,

    I'm sorry your first round taking Clomid didn't work and that you got a yeast infection on top :-/ Maybe you could try this cycle just without Clomid? I think I would be too much afraid of missing THE month for making a break... But I tend to approach things from the pessimistic side ;-) I wish you all the best no matter how you decide! At least you don't have to worry about malformations anymore thanks to atomic's answer. Please let me know how it's going on with you.

    Verena

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  3. #13
    Quote Originally Posted by atomic sagebrush View Post
    Keep in mind, in that case, that if something were to go wrong (such as a loss, G-- forbid, or a side effect - we have only ever had mild ones, or an allergic reaction - never had one happen but they are possible) and you're in the ER with him, they're going to ask you what medication you were on if any and then that puts you in a heck of an awkward position.

    Femara did seem better in one study, but studies are funny things in that sometimes one will say one thing, and another study will say the opposite. There are more studies that support Clomid on its own, and only the one in which it was compared to Femara.

    I believe Femara is better, although it can be harder to come by as not all docs are willing to prescribe it.
    Heck, you are right. Didn't think about that. Then I might try to discuss it with him. There's also the small chance for multiples and I would feel really bad if we end up having twins and I didn't inform him. That would really feel like cheating...

    My doc is quite open and in the past he always prescribed everything I asked him for. So if I decide (together with DH ;-)) to go for it, I'll ask him for Femara first.

    Thank you again, atomic!!

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  4. #14
    Quote Originally Posted by atomic sagebrush View Post
    Keep in mind, in that case, that if something were to go wrong (such as a loss, G-- forbid, or a side effect - we have only ever had mild ones, or an allergic reaction - never had one happen but they are possible) and you're in the ER with him, they're going to ask you what medication you were on if any and then that puts you in a heck of an awkward position.

    Femara did seem better in one study, but studies are funny things in that sometimes one will say one thing, and another study will say the opposite. There are more studies that support Clomid on its own, and only the one in which it was compared to Femara.

    I believe Femara is better, although it can be harder to come by as not all docs are willing to prescribe it.
    Hi atomic,

    I tried to find that study comparing femara and clomid concerning sex ratio but I couldn't find it. Do you have it and could share it with me? Or did you mean in your answer that femara is the better option in general, not only for swaying?

    Thank you :-)

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  5. #15
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    It is the better option in general. Better for fertility, fewer side effects, less chance of multiples.

    Do you really need to see all the studies, or can you take my word that I have seen and read the studies? It is really time consuming to look up studies for you guys and I've kind of decided not to do it any more. I have no motivation in promoting one medication over the other, I don't own stock in Femara or anything, LOL.
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  6. #16
    .
    Last edited by SoFullofHope; April 26th, 2018 at 03:45 PM.

  7. #17
    Quote Originally Posted by atomic sagebrush View Post
    It is the better option in general. Better for fertility, fewer side effects, less chance of multiples.

    Do you really need to see all the studies, or can you take my word that I have seen and read the studies? It is really time consuming to look up studies for you guys and I've kind of decided not to do it any more. I have no motivation in promoting one medication over the other, I don't own stock in Femara or anything, LOL.
    You don't have to look the study up, no problem. I thought maybe it's saved in some forum here and I just didn't find it. I also thought there are some conrete numbers about the sex ratio after using clomid and femara, but if I understand you correctly, it's just a general comparison.

    I guess I'm just slightly nervous asking my doc for femara, because clomid is incorporated in the girl sway statistics, but femara isn't. But I'll try to believe you without seeing numbers with my own eyes ;-)

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  8. #18
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    It is, that's the dumb thing!! It is on here somewhere but I have sooooo many posts that it's really hard for me to find anything I posted (because I have to scroll through tons of other posts) and then when I Google things, it's all so vague that again, I have to look and look and look because there are so many studies done that the one I want gets lost in the shuffle. It takes me tons of time.

    The Femara study is just one study. There are more studies that show Clomid sways pink, and only the one on Femara. Femara is only just coming into popularity so as more use it, we'll have more info to go on.
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  9. #19
    I'd imagine as Femara lowers estrogen, that is where it could theoretically sway pink?

    I'm mostly popping in because my RE suggested it and I want a boy and did some research on it.

  10. #20
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    Quote Originally Posted by Throwaway_panther View Post
    I'd imagine as Femara lowers estrogen, that is where it could theoretically sway pink?

    I'm mostly popping in because my RE suggested it and I want a boy and did some research on it.
    That's what I would think, but the thing is that Femara lowers estrogen less where it counts Letrozole For Ovulation Assistance, Alternatives To Clomid and we had originally expected it would be more blue friendly than Clomid. That it isn't, makes me question how any of it works and we honestly don't know at all so when in doubt I like you guys to do what seems to work, and not what theories say should work, since all our theories, even mine, are based on a pittance of info sadly.
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