Need advice, not ovulating I think :(

[maidentomother]

No it doesn't, Femara may even increase quality.

FWIW, while I agree that Clomid is best avoided by older women (due to its potential to thin the uterine lining, at the very least, if not possibly for other reasons as well), I don't believe it can negatively affect egg quality in women of any age. There is no evidence supporting that idea, if anything rather some that suggests both Clomid & Femara can improve the quality of egg that is released as well as other factors that up odds of conception, in general.

[Traci25]

That's interesting, il let you know what Ob says but it seems as femara has better outcome than clomid I could be wrong! I'm just praying for a healthy baby and dd would my lottery!! I'm sure I missed it this month but hoping for next month!
I've learned so much on this website it's amazing! I had no idea about list stuff!

[atomic sagebrush]

There actually is plenty of evidence that Clomid can raise FSH to such an extent that it causes egg quality to tank. I have seen people with FSH of 7 go onto Clomid and suddenly within 2 months their FSH is in the 30's. Some doctors like to tell people, "that was happening anyway" but it's happened to thousands of people who then went off Clomid and had their FSH return to normal and now most doctors do recognize that it's not right for everyone. It's something that a person with already highish FSH like 10 or above should not be on and most of us ladies "of a certain age" may do better on another medication.

[atomic sagebrush]

Thank you all! That's great info. I will forgo vitex and clomid, if I can't concierge next few months il ask for femera I have an amazing ob she conceived her
Last In her 40's so she totally gets it. I'm gonna dtd like atomic
Said and then if bfn go for femera. I did look at Ivf but the results look bad at viable embryos. If I can get a dd i would
Be over the moon but I do have 3 healthy kids
That I feel so blessed with. I adore this site and all the amazing women I feel so blessed to find it! Just to verify femera doesn't decrease quality of eggs?

Femara is better all around. THe downside of Femara is that it has to be used off label, meaning it hasn't been approved for fertility uses and so you can't always find a doctor who is informed and willing to prescribe it.

maiden, you probably know this but chemically what is the difference between Clomid and Femara that prevents Femara from causing the issues that Clomid can???

[maidentomother]

I'll do some research, but I know one HUGE factor is the dramatic difference in half-lives, I.e. how long each drug lasts in the body. Clomid has a much, much longer half-life than Femara so the estrogen blocking effects are much more long-lived too. Femara acts more like a quick trigger; after you stop taking it your hormones rebound and (over)compensate then quickly return to normal. With Clomid, there's a much longer estrogen blocking effect which the body often can't recover from as easily/quickly so you can see more serious issues that develop due to long term low/suppressed estrogen. Plus, the hormonal rebound on Clomid is generally weaker than on Femara bc there is no real break from the estrogen blocking effect; thus why many women who respond poorly or not at all to Clomid do well on Femara.

And that's not even addressing potential effects on progesterone levels, and surely there IS an effect simply bc of how interactive/interdependent E & P are. Like dance partners as atomic recently described so eloquently.

Hope that makes sense! I definitely want to learn more about their differences as that may shed light on why Femara may sway pink even more than Clomid, at least in some groups of women (PCOS).

[atomic sagebrush]

I am very curious about that as well for the reason that on paper, using old school sway tactics, Clomid "ought to" sway blue (because it raises T and blocks estrogen) In fact they used to be down on it on IG and some blue swayers were even thinking about getting it, another example of the pitfall where people get so hung up on the speculative reasons of why things are supposed to sway that they lose sight of just doing what is actually WORKING (because when I read the studies, it was profoundly obvious to me that Clomid on its own was swaying at least 3-5% because that's what was found in several studies)

[maidentomother]

And they just ignored the drying effect of Clomid? Seriously? I'm 2dpo on my first Clomid cycle and I have never been so dry except for on birth control. Thankfully I had SOME EWCM for about 24 hours.

Btw, I've noticed that my body produces a lot more EWCM in response to sex/exposure to semen. Like, 6 hours later, BAM I have globs of it, even if I was really dry/had infertile CM before. That time frame is pretty consistent too, 6 hours. It is generally in my fertile period but cycles when I was swaying but not TTC I usually have less EWCM.

I'll let you know what I find. I really miss being at university and having access to unlimited free studies! And it's so expensive to subscribe as a private individual.

[atomic sagebrush]

You prob. already saw that study from about a month ago that showed more intercourse = higher rate of conception, I also notice that too. Even in my LP sometimes if we're having lots of fun I find I"m much more in the mood with EWCM. Bodies are weird LOL.

I'm sure on IG they thought they could just use egg whites and somehow that would magically be the same thing. But no.

[1moregirl]

You prob. already saw that study from about a month ago that showed more intercourse = higher rate of conception, I also notice that too. Even in my LP sometimes if we're having lots of fun I find I"m much more in the mood with EWCM. Bodies are weird LOL.

I'm sure on IG they thought they could just use egg whites and somehow that would magically be the same thing. But no.

Atomic - is this the theory behind more BD equals higher chances of conception equals higher odds of a boy? So that's why it's recommended just one BD shot to sway girl? Soooo interesting....Good Lord - imagine if you used egg whites for lube and came up with an allergic reaction down there? Youch - not nice.

[atomic sagebrush]

Atomic - is this the theory behind more BD equals higher chances of conception equals higher odds of a boy? So that's why it's recommended just one BD shot to sway girl? Soooo interesting....Good Lord - imagine if you used egg whites for lube and came up with an allergic reaction down there? Youch - not nice.

Weirdly, no it isn't. My original thinking was based on studies dating back to 1800's that women who have a regular, live in male partner have more sons, plus the fact that release every 2-4 days = max sperm numbers and also men having regular sex (not release, but sex) may have higher T and sperm count as well. Then this study came out a month ago and added yet another twist on that because everything that ups fertility, seems to sway blue.

The big concern i have with the egg whites is salmonella. It can 100% live in the repro tract of female mammals and it causes miscarriage in animals so I feel very much to be avoided.