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Archive for embryos

Can you PGD previously frozen embryos from a past IVF cycle?

by Gender Selection Guru
November 1st, 2013

We get this question emailed to us a lot- We have X number of frozen embryos (from our fresh IVF cycle in 20XX) they are 5 day old blasts(or 3 day old blasts). We have a boy and are expecting our second boy this November. Thinking ahead we are wondering if we could do PGD testing on any of our frozen embryos to see if there is a girl in there or not.

Yes you can!

Many infertility patients have soldiered through cycles and acheived their dreams of having a child or two and still have frozen embryos available.  It’s difficult to find the actual number of embryos currently on ice in the United States but various sources have reported 500,000 to over 1 million embryos that are frozen today.

If you have frozen embryos and a family of same gendered children or an unbalance and you have dreams of achieving some balance, the science is there and you can have your embryos thawed and biopsied to test for gender along with all other chromosomes as well.  Embryos frozen on day 3 or day 5 can be biopsied and not have to be refrozen before transfer based on the PGD method used.

We have all of the details within our forum and we hope you will join us to find out more information and find a clinic near you!  We can even help you book a consult with a doctor that can help you!

Gender Dreaming Forums

Categories Elective IVF for Gender Selection

Traveling from Australia for Gender Selection- IVF/PGD Overseas

by Gender Selection Guru
May 5th, 2013

If you are from Australia and are seeking to balance your family with a daughter or son, we have a very large community here at GenderDreaming.com that will guide you through the process.  We can assist with finding local doctors to begin the process as well as helping you select the best clinic outside of Australia for you.

It’s not about “Designer Babies”, it’s not about skewing the gender ratio of our societies, it is about seeking balance within our own lives and our own families and just as choosing to have another child is our rights as individuals, so is choosing to only have that child if it is a particular gender.  Most of us already have 2,3,4 of the same gender and are not open to trying again naturally.  It’s not about choosing to have a son as a first-born.

It is a responsible decision to seek out IVF/PGD before an embryo is implanted rather than go about things the old-fashioned way and then choose to abort because the “baby is the wrong gender”.  Termination due to gender is NOT supported on www.GenderDreaming.com and you will not find any information regarding that topic.  We support the responsible and sensible approach of using modern technology to select the healthiest embryo and the correct gender prior to transfer and implantation.  Often times, extra embryos are donated to other couples that are seeking to have a baby due to infertility reasons.

So, there is support, via the Internet, within our forums.  There are thousands like you if you are looking for where to begin and we are happy to assist.

The IVF/PGD forums are Member-only and thus private from Google searches and anyone casually browsing the site.  You must first register and then become a Dream Member to gain access to all of the information.  But it is here!  We can help you navigate the world of IVF/PGD and help you bring home your dream baby!

Categories Elective IVF for Gender Selection
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Day 5 Biopsy with PGD

by Gender Selection Guru
May 3rd, 2013

Do you Day 5?  If not, your program is going to get left behind. Day 5 biopsy seems to have overtaken Day 3 PGD across most of the leading IVF centers in the US.  There were so many issues surrounding Day 3 biopsy, Day 5 seems to be a much better option.

Recently, trophectoderm biopsy is gaining popularity as an alternative method of embryo biopsy. Since trophectoderm cells are extra-embryonic tissue, they do not become part of the fetus but do become part of supporting structures, such as the placenta and membranes. Trophectoderm biopsy takes place at the blastocyst (day 5 or 6) stage of development, as the trophectoderm is beginning to herniate through the zona pellucida. Instead of removing an individual blastomere or cell, several trophectoderm cells are removed.

Day 5 Pros-

  • Since the embryo is further along in development, mosacism should be lessened at this point
  • Using Natera or aCGH, all chromosomes can be reviewed hopefully increasing the pregnancy rate.
  • Cells are removed from what will become the placenta and not one of only 6-8 cells like on day 3 which may be easier on the embryo.
  • Lower number of embryos may be transferred when all chromosomes are evaluated for health leading to fewer high-risk pregnancies

Day 5 Cons-

  • An embryo must become a blastocyst and have the trophoderm layer that becomes the placenta from which the cells are taken on day 5.
  • If the embryo does NOT reach blastocyst stage on day 5 and takes until day 6, the embryo must be frozen and a later Frozen Embryo Transfer(FET) must be performed.
  • Because of the high rate of abnormals with IVF, a risk of a no-transfer is higher with a day 5 biopsy due to reduced numbers. Natera’s website states that a transfer is likely with minimum of 8 embryos biopsied- this does NOT take the gender selection into consideration though which means our chances at transfer are reduce beyond their quoted rates.
  • Confined placental mosaicism (CPM) represents a discrepancy between the chromosomal makeup of the cells in the placenta and the cells in the baby. It is estimated to occur in 1-2% of pregnancies where the placenta contains abnormal cells but the embryo is normal.
So, if you do not yet have Day 5 biopsy capability you better get with the program because that is where the highest pregnancy rates are coming from on GenderDreaming.com.  If you don’t have Day 5 biopsy capability, you are no longer on the list of possible clinics for most cyclers in the US.
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