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  1. January 9th, 2014, 03:55 PM #1
    Agnes
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    Immune treatment

    Hello,
    Thank you for this forum!!! I need your help, please!
    I have three boys (easily conceived) - NATURAL pregnancies. I'm 39 years old.
    Two years ago I was wondering to give one girl to my beautiful family. But this is not as easy...
    I am seeking your insight on the captioned matter and possible next steps. I've done 4 transfers (PGD) in the past 2 years time period of which all resulted in negative betas..
    1st transfer: morula (poor quality) no surprise (day3 Natera biopsy/day5TR)
    2nd transfer: day6 fresh Natera transfer (HB ; day5 Natera biopsy/day6TR)
    3rd transfer: FET (HB ; day5 Natera biopsy)
    4th transfer: FET (HBab, day5 Natera biopsy)
    I have had a hysteroscopy prior to my 4th transfer and it was fine, no polyp or fibroid but we did 3 months of Lupron Depot to get better lining and my immune treatment was: Lovenox, steroid, babyasa, IVIG (2x20gm).
    What's wrong with me? Is this an implantation issue, egg quality ("old eggs"), immune issue or just bad luck..? I can not afford more IVIG therapy so I hope there is some alternative treatment (...) but do I really need it??? The big "gun"?!
    I still have one more "fair" quality embryo (HBbc) on ice.. Transfer her first or do another fresh cycle? Do I have a bigger chance with donor egg?
    I was wondering if you had any thoughts on this results..
    Thanks in advance!!!
    Agnes

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    Last edited by Agnes; January 11th, 2014 at 01:11 PM.
    +

    Cycle 1: HRC June 2012 Long Lupron 1XY NT What?! 9boys from 11?! Only one normal XY.
    http://genderdreaming.com/forum/cycl...nsfer-hrc.html
    Cycle 2: HRC Aug 2012 Microdose Lupron with Growth Hormone Day3 Natera Morula XX BFN Poor quality.
    http://genderdreaming.com/forum/cycl...2-hrc-bfn.html
    Cycle 3: HRC Dec 2012 Antagonist with GH + Metformin Day5 Natera 6 normals!!! (3:3) BFN (no more Natera Day6 Fresh Tr)
    http://genderdreaming.com/forum/cycl...3-hrc-bfn.html
    FET 1 : HRC February 2013 BFN oh, yes!
    http://genderdreaming.com/forum/showthread.php?t=25611
    Cycle 4: HRC April/May 2013 Antagonist with GH + Metformin Cancelled (only 4 days on stims / cyst)
    http://genderdreaming.com/forum/west...cancelled.html.
    Cycle 4 1/2: HRC June 2013 Antagonist with GH + Metformin 2XY NT Boo! Hahaha..Hahahaha.. http://genderdreaming.com/forum/west...normal-xy.html
    Cycle 5: HRC, Planned FET (Natera)
    http://genderdreaming.com/forum/west...normal-xx.html 2XY+1XX
    3 months of Lupron Depot to get better lining (hysteroscopy).
    FET 2 : HRC Dec 2013 BFN
    http://genderdreaming.com/forum/west...oas-bfn-7.html
    Cycle 6: HRC March 2014 (IviGen) Day6 fresh transfer / BFP
    http://genderdreaming.com/forum/west...saw-hb-46.html
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  2. February 3rd, 2014, 11:49 AM #2
    Agnes
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    BUMP!
    +

    Cycle 1: HRC June 2012 Long Lupron 1XY NT What?! 9boys from 11?! Only one normal XY.
    http://genderdreaming.com/forum/cycl...nsfer-hrc.html
    Cycle 2: HRC Aug 2012 Microdose Lupron with Growth Hormone Day3 Natera Morula XX BFN Poor quality.
    http://genderdreaming.com/forum/cycl...2-hrc-bfn.html
    Cycle 3: HRC Dec 2012 Antagonist with GH + Metformin Day5 Natera 6 normals!!! (3:3) BFN (no more Natera Day6 Fresh Tr)
    http://genderdreaming.com/forum/cycl...3-hrc-bfn.html
    FET 1 : HRC February 2013 BFN oh, yes!
    http://genderdreaming.com/forum/showthread.php?t=25611
    Cycle 4: HRC April/May 2013 Antagonist with GH + Metformin Cancelled (only 4 days on stims / cyst)
    http://genderdreaming.com/forum/west...cancelled.html.
    Cycle 4 1/2: HRC June 2013 Antagonist with GH + Metformin 2XY NT Boo! Hahaha..Hahahaha.. http://genderdreaming.com/forum/west...normal-xy.html
    Cycle 5: HRC, Planned FET (Natera)
    http://genderdreaming.com/forum/west...normal-xx.html 2XY+1XX
    3 months of Lupron Depot to get better lining (hysteroscopy).
    FET 2 : HRC Dec 2013 BFN
    http://genderdreaming.com/forum/west...oas-bfn-7.html
    Cycle 6: HRC March 2014 (IviGen) Day6 fresh transfer / BFP
    http://genderdreaming.com/forum/west...saw-hb-46.html
    Reply With Quote Reply With Quote
  3. February 3rd, 2014, 12:10 PM #3
    Dr. Braverman
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    Big Smile This may be an implantation issue.

    Quote Originally Posted by Agnes View Post
    Hello,
    Thank you for this forum!!! I need your help, please!
    I have three boys (easily conceived) - NATURAL pregnancies. I'm 39 years old.
    Two years ago I was wondering to give one girl to my beautiful family. But this is not as easy...
    I am seeking your insight on the captioned matter and possible next steps. I've done 4 transfers (PGD) in the past 2 years time period of which all resulted in negative betas..
    1st transfer: morula (poor quality) no surprise (day3 Natera biopsy/day5TR)
    2nd transfer: day6 fresh Natera transfer (HB ; day5 Natera biopsy/day6TR)
    3rd transfer: FET (HB ; day5 Natera biopsy)
    4th transfer: FET (HBab, day5 Natera biopsy)
    I have had a hysteroscopy prior to my 4th transfer and it was fine, no polyp or fibroid but we did 3 months of Lupron Depot to get better lining and my immune treatment was: Lovenox, steroid, babyasa, IVIG (2x20gm).
    What's wrong with me? Is this an implantation issue, egg quality ("old eggs"), immune issue or just bad luck..? I can not afford more IVIG therapy so I hope there is some alternative treatment (...) but do I really need it??? The big "gun"?!
    I still have one more "fair" quality embryo (HBbc) on ice.. Transfer her first or do another fresh cycle? Do I have a bigger chance with donor egg?
    I was wondering if you had any thoughts on this results..
    Thanks in advance!!!
    Agnes

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    Yes there could certainly be an implantation issue here as you have met the definition by failing with good quality embryos and having a normal uterine cavity. Best would be to fill out a consult request on my website and we will schedule a free 10 minute chat to reveiw your case and how I can help you.
    Dr. Braverman, Founder and Medical Director at Braverman Reproductive Immunology, New York
    www.preventmiscarriage.com
    @BravermanReprod
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  4. February 3rd, 2014, 04:36 PM #4
    Agnes
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    Thank you!!!
    +

    Cycle 1: HRC June 2012 Long Lupron 1XY NT What?! 9boys from 11?! Only one normal XY.
    http://genderdreaming.com/forum/cycl...nsfer-hrc.html
    Cycle 2: HRC Aug 2012 Microdose Lupron with Growth Hormone Day3 Natera Morula XX BFN Poor quality.
    http://genderdreaming.com/forum/cycl...2-hrc-bfn.html
    Cycle 3: HRC Dec 2012 Antagonist with GH + Metformin Day5 Natera 6 normals!!! (3:3) BFN (no more Natera Day6 Fresh Tr)
    http://genderdreaming.com/forum/cycl...3-hrc-bfn.html
    FET 1 : HRC February 2013 BFN oh, yes!
    http://genderdreaming.com/forum/showthread.php?t=25611
    Cycle 4: HRC April/May 2013 Antagonist with GH + Metformin Cancelled (only 4 days on stims / cyst)
    http://genderdreaming.com/forum/west...cancelled.html.
    Cycle 4 1/2: HRC June 2013 Antagonist with GH + Metformin 2XY NT Boo! Hahaha..Hahahaha.. http://genderdreaming.com/forum/west...normal-xy.html
    Cycle 5: HRC, Planned FET (Natera)
    http://genderdreaming.com/forum/west...normal-xx.html 2XY+1XX
    3 months of Lupron Depot to get better lining (hysteroscopy).
    FET 2 : HRC Dec 2013 BFN
    http://genderdreaming.com/forum/west...oas-bfn-7.html
    Cycle 6: HRC March 2014 (IviGen) Day6 fresh transfer / BFP
    http://genderdreaming.com/forum/west...saw-hb-46.html
    Reply With Quote Reply With Quote
  5. February 3rd, 2014, 05:45 PM #5
    nuthinbutpink
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    Braverman Consult
    Last edited by nuthinbutpink; February 3rd, 2014 at 05:47 PM.
    Mom to

    and my IVF/PGD

    It's better to look back on life and say: "I can't believe I did that" than to look back and say "I wish I did that".

    New to IVF/PGD for Family Balancing? Read this- Understanding IVF/PGD- a HT Guide for those New to the IVF/PGD Process

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