Anyone do Femara/IUI

[HealthyGirl]

Maidentomother what do you mean by not too few attempts?




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[atomic sagebrush]

A large number of RE's will not do IUI any more because it doesn't work. It is hard to give useful stats because so many people are doing IUI who have fertility issues but here's one article that discusses some of the studies that were done that show piss poor odds of conception. What Is the IUI Success Rate in Pregnancy?

Unfortunately for insurance purposes many docs HAVE to do 3 cycles IUI before they can move on to IVF. I do not think it's a good idea for anyone with egg quality issues because the real issue is just "waiting for Goldie" and not "unexplained infertility". Low AMH, high FSH is NOT unexplained infertility, that is explained LOL. BUT some doctors may pursue this because they want to get your insurance to pay for IVF eventually. THat may or may not be in your best interest.

The problem I have with it is that most people do IUI PLUS intercourse and that ends up being more than one attempt in fertile window. And in terms of stats no one really knows which BD was the one that did it, so IUI may even have WORSE pg rates than we realize.

[atomic sagebrush]

Wow maiden! I honestly didn't realize all of that. I thought the success rate was pretty high. If I do remember correctly it does sway boy more. But why is that?

We don't know why it is. And in fact the overall numbers (like with Clomid) do not make this obvious, we know of people who did IUI and got girls (keep in mind that . BUT the reason why we DO know it sways pretty strongly is because we have old studies on timing. In these studies, people were either given Clomid and told to DTD 3 days before "ovulating" (keeping in mind that this is actually impossible because as we all know, Clomid can totally change the day you O, but I digress) or NOT given medication at all and just brought in for IUI on O day. The Clomid group got overwhelmingly more girls, the IUI group got overwhelmingly more boys, and since new and better ovulation detecting technology has shown 50-50 boys and girls conceived every day of the cycle, timing has to be removed as a variable leaving only the Clomid and IUI to be swaying.

[atomic sagebrush]

Really appreciate the response maidentomother.

Our RE told us femara with TIC will probably be like trying naturally on our own.

He also said IUI doesn't work when it's a male issue and it's used for unexplained infertility as in our case.
I completely agree with you that it's just a scam but I did one cycle on femara unmonitored ( my husband and RE don't know ) and we bd every 3 days that cycle and it ended in a bfn and that's why I'm not very hopeful.
My insurance pays for the IUI so I thought it might be worth a shot.

Is there a reason why it sways boy? Does it depend on which sperm washing technique they use at all?
One of the questions my husband asked him today was about whether it favors one gender over the other. We are still waiting on a response.





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I know you've asked me about this several times HG and I think I probably should have been firmer about it at the beginning but you are taking the "sperm washing may matter" idea way too seriously. It was (as all these things are) a small, statistically significant difference in one study done ages ago, but it DOESN'T WORK or else all the RE's would be using it. Even with washing and spinning and swimming up and down, Ericsson method does not get different than 50-50 X and Y sperm and he has admitted this, but claims that the sperm go on to make different % of XX and XY babies - still about the same we are getting with swaying + fertility medication. No better, and it may very well be the fertility medication doing that anyway.

So the idea you keep coming back to in your mind, that somehow just doing the washing will do anything at all tangible - it just can't matter really. And the reason why they use the washing methods they do is because certain washing methods make much lower odds of conception than other methods do and I think it is just best, since rates of conception are not great with IUI to begin with, to stick to the washing methods that your doctor has seen best conception rates with and not chase a ghost from a study that was done like 30 years ago on these washing methods. If they worked in any reliable way, all the doctors would be doing it. I am just really concerned that you have this idea in your mind that you'll do IUI with some washing method and end up having a girl but it does not work that way. I am afraid you are lowering both your chances of conception and chances of pink.

Sorry I hope that isn't overly harsh, I am just really concerned we are on the cusp of a mistake here.

[atomic sagebrush]

Thanks Maidentomother.
We are gonna go for timed intercourse but don't know if I should do every 3 days or eve 3 days plus additional attempt at pod opk.
I did every 3 days on femara ( unmonitored)for one cycle and it's ended in bfn.
My RE decided to put my on 5 mg of femara this cycle.

Btw did I understand you correctly in June 2ww when you said you were conceived through IUI?


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You have to keep in mind though that with low AMH, high FSH, you may not have gotten a good, fertilizable egg that month. I just feel like you're thinking that if you did one thing one month, that means you have to cross it off a checklist or something and that is just not the case. It takes fully fertile couples with ideal numbers, doing nothing to sway, an average of 3-6 months to get pregnant.

So you don't even know that every 3 days can't or won't work for you, just that it didn't work in one month when you tried it. I'm not trying to be flip or discount your concerns in any way, it is that I have seen tons of people walk down this road and jump to conclusions on the basis of one month's results that something can't work for them when we do not even know that's the case.

Unfortunately my crystal ball is in the shop this week so I do not know what the right answer is. For best chance of pink, stick with every 3 days. if you want better odds of conception (bearing in mind that BFN may have nothing to do with your BD pattern and everything to do with your numbers) then add attempt at pos OPK.

[The Anchor]

I'll pipe up because my numbers were almost exactly the same as yours. And RE mentioned IUI, and because it was covered by insurance, I went for it. First round, chemical. Second, they had me trigger way too early, and I didn't ovulate at all. RE sheepishly said it's not a matter of me ovulating, I can do that fine on my own, it's the quality of the eggs. I'm 42. Trying naturally is my only option now.

I KNOW its my eggs. My uterus and tubes are in great shape. Fairly regular cycles. Monitored and only one cyst in 2 1/2 years (which cleared up on its own). SA says DH is GREAT. And both bubs are OHWs.

[Keshet]

I would like to add my opinion that I disagree that IUI is a scam. I did IUI with injectibles in order to get more eggs because of my older age and I did get pregnant twice with IUI. It did end up with miscarriage, but I did conceive. I ended up doing TI with different injectibles on my last try and it worked. But, I took that route simply because I had no insurance coverage and it was purely a financial decision. So I think that if you are talking about woman's age as the limiting factor success will have more to do with how many eggs you stimulate on your particular medication protocol than the IUI procedure--unless the issue is related to sperm function.

[maidentomother]

Keshet, it was almost certainly the injectables that got you pregnant, NOT the IUIs. That's another reason IUI seems better than it is, bc it's often paired with the first time use of injectables. It's more/better eggs that improve your adds, nothing to do with sperm. Drs are just locked into this rigid formula bc most don't think outside the box or question things adequately.

[Keshet]

I agree that it was the injectibles that did the trick in my case, but both the Iui and TI worked to get the sperm in the right place. I didn't do any worse with IUI. In some ways, It was helpful for me to have the timing more closely watched in the IUI cycle. Also, it was harder for ensure that DH was in the right mood to do TI at the right time when there wasn't a doctor overseeing it. But thankfully it all worked out in the end.

[HealthyGirl]

Keshet did you ever do femara/clomid with TI?

What method gave you your BFP?
Also did your RE run any tests and would love to know your numbers if you don't mind sharing.

Thx


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