IVF :: Page 2 :: Natural Gender Selection, IVF/PGD Experts

Can you PGD previously frozen embryos from a past IVF cycle?

November 1st, 2013

We get this question emailed to us a lot- We have X number of frozen embryos (from our fresh IVF cycle in 20XX) they are 5 day old blasts(or 3 day old blasts). We have a boy and are expecting our second boy this November. Thinking ahead we are wondering if we could do PGD testing on any of our frozen embryos to see if there is a girl in there or not.

Yes you can!

Many infertility patients have soldiered through cycles and acheived their dreams of having a child or two and still have frozen embryos available. It’s difficult to find the actual number of embryos currently on ice in the United States but various sources have reported 500,000 to over 1 million embryos that are frozen today.

If you have frozen embryos and a family of same gendered children or an unbalance and you have dreams of achieving some balance, the science is there and you can have your embryos thawed and biopsied to test for gender along with all other chromosomes as well. Embryos frozen on day 3 or day 5 can be biopsied and not have to be refrozen before transfer based on the PGD method used.

We have all of the details within our forum and we hope you will join us to find out more information and find a clinic near you! We can even help you book a consult with a doctor that can help you!

Gender Dreaming Forums

Categories Elective IVF for Gender Selection

Day 5 Biopsy with PGD

by Gender Selection Guru

May 3rd, 2013

Do you Day 5? If not, your program is going to get left behind. Day 5 biopsy seems to have overtaken Day 3 PGD across most of the leading IVF centers in the US. There were so many issues surrounding Day 3 biopsy, Day 5 seems to be a much better option.

Recently, trophectoderm biopsy is gaining popularity as an alternative method of embryo biopsy. Since trophectoderm cells are extra-embryonic tissue, they do not become part of the fetus but do become part of supporting structures, such as the placenta and membranes. Trophectoderm biopsy takes place at the blastocyst (day 5 or 6) stage of development, as the trophectoderm is beginning to herniate through the zona pellucida. Instead of removing an individual blastomere or cell, several trophectoderm cells are removed.

Day 5 Pros-

Since the embryo is further along in development, mosacism should be lessened at this point
Using Natera or aCGH, all chromosomes can be reviewed hopefully increasing the pregnancy rate.
Cells are removed from what will become the placenta and not one of only 6-8 cells like on day 3 which may be easier on the embryo.
Lower number of embryos may be transferred when all chromosomes are evaluated for health leading to fewer high-risk pregnancies

Day 5 Cons-

An embryo must become a blastocyst and have the trophoderm layer that becomes the placenta from which the cells are taken on day 5.
If the embryo does NOT reach blastocyst stage on day 5 and takes until day 6, the embryo must be frozen and a later Frozen Embryo Transfer(FET) must be performed.
Because of the high rate of abnormals with IVF, a risk of a no-transfer is higher with a day 5 biopsy due to reduced numbers. Natera’s website states that a transfer is likely with minimum of 8 embryos biopsied- this does NOT take the gender selection into consideration though which means our chances at transfer are reduce beyond their quoted rates.
Confined placental mosaicism (CPM) represents a discrepancy between the chromosomal makeup of the cells in the placenta and the cells in the baby. It is estimated to occur in 1-2% of pregnancies where the placenta contains abnormal cells but the embryo is normal.

So, if you do not yet have Day 5 biopsy capability you better get with the program because that is where the highest pregnancy rates are coming from on GenderDreaming.com. If you don’t have Day 5 biopsy capability, you are no longer on the list of possible clinics for most cyclers in the US.

Categories Uncategorized
Comments (0)

Tips for IVF/PGD for Family Balancing

by nuthinbutpink

April 14th, 2013

Can you test(biopsy and PGD) previously frozen embryos?

Yes! If you have already been through IVF and have frozen embryos from a past cycle, it is possible to thaw and test those embryos for both health and gender.

Watch your Weight!

Researchers found that women classed as ‘overweight’ had a 24 percent extra risk of miscarriage compared with a normal pregnancy, and a 9 percent lower chance of having a baby.

For ‘obese’ women, the risk of miscarriage was increased by 40 percent and chance of a live birth cut by 20 percent.

“The higher up the (BMI) range, the more likely it is that overall success rate will be reduced,” the Daily Mail quoted El-Toukhy as saying.

“To maximise the chance of a successful pregnancy, we are now recommending that women get as close as possible to a healthy weight before starting treatment,” he added.

His Diet Matters Too!

Better sperm quality and hence higher chances of a successful in-vitro fertilization with men who eat plenty of fruits and grains, but cut down on their red meat and alcohol intake, has been reported in a new study.

The study revealed that a poor diet and obesity can lower sperm concentration and affect their ability to swim towards an egg.

In the past, female fertility problems have been linked to obesity as well as smoking and drinking, but it was not clear until now if the same applies to men as well.

The latest study of men with partners, who were undergoing a type of fertility treatment, has revealed that those who regularly binged on alcohol and ate poorly were slowed down on the fertility front, the Daily Mail reported.

Frozen Embryo Transfers May Yield Better Results

Many recent studies are showing that the live birth rate after a planned frozen transfer is significantly higher than a fresh transfer following IVF stimulation. The clinical pregnancy rate per transfer was significantly greater in the cryopreservation group than in the fresh group. These results strongly suggest impaired endometrial receptivity in fresh ET cycles after ovarian stimulation, when compared with FET cycles with artificial endometrial preparation. Impaired endometrial receptivity apparently accounted for most implantation failures in the fresh group.

Categories Uncategorized